Anticorps Polyclonal de lapin anti-GEFT

• Phare
• Validé par KD/KO

GEFT Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 51004-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 51004-1-AP (same clone as 51004-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 51004-1-AP (GEFT antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 51004-1-PBS in a different storage buffer formulation.

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Informations sur le produit

51004-1-PBS cible GEFT dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: RhoA/RAC/CDC42 exchange factor
• Masse moléculaire calculée: 64 kDa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: BC047559
• Symbole du gène: GEFT
• Identification du gène (NCBI): 115557
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

GEFT, also named as p63RhoGEF, may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases. GETF links specifically G alpha q/11-coupled receptors to RHOA activation. GEFT may be an important regulator of processes involved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1. It is involved in skeletal myogenesis. GEFT is expressed as three isoforms (64, 53 and 68kDa).

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