Anticorps Polyclonal de lapin anti-GGTLC1

• Phare
• Validé par KD/KO

GGTLC1 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17537-1-PBS

Synonymes

Gamma-glutamyltransferase light chain 1, Gamma-glutamyltransferase-like activity 4, Gamma-glutamyltransferase-like protein 6, GGTL6, GGTLA4

---

Galerie de données de validation

• 

  WB analysis of HepG2 using 17537-1-AP (same clone as 17537-1-PBS)

  WB result of GGTLC1 antibody (17537-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-GGTLC1 transfected HepG2 cells. This data was developed using the same antibody clone with 17537-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 17537-1-AP (same clone as 17537-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17537-1-AP (GGTLC1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17537-1-PBS in a different storage buffer formulation.

• 

  IF Staining of HepG2 using 17537-1-AP (same clone as 17537-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using GGTLC1 antibody (17537-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 17537-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

17537-1-PBS cible GGTLC1 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: GGTLC1 Protéine recombinante Ag11592
• Nom complet: gamma-glutamyltransferase light chain 1
• Masse moléculaire calculée: 225 aa, 24 kDa
• Poids moléculaire observé: 24 kDa
• Numéro d’acquisition GenBank: BC040904
• Symbole du gène: GGTLC1
• Identification du gène (NCBI): 92086
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Gamma-glutamyltransferase light chain 1 (GGTLC1), initially named GGTL6, then GGTLA4, and later GGTLC1 in 2008, is a member of the gamma-glutamyl transferase (GGT) family. The most ubiquitously expressed human GGT gene, GGT1, encodes a single transmembrane polypeptide that is post-translationally processed to form a heavy and a light chain. Knockdown of GGTLC1 in Endometrial cancer (EC) cells was shown to induce G0/G1 phase arrest and apoptosis, underscoring the significance of GGTLC1 as a key regulator of these cellular processes in EC (PMID: 38841516).

{{ptg:RelatedPrimaryAntibodies}}