Anticorps Recombinant de lapin anti-GGTLC1

• Phare
• Validé par KD/KO

GGTLC1 Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

240297D9

N° de cat : 83392-3-PBS

Synonymes

240297D9, Gamma-glutamyltransferase light chain 1, Gamma-glutamyltransferase-like activity 4, Gamma-glutamyltransferase-like protein 6, GGTL6

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Galerie de données de validation

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  WB analysis of HepG2 using 83392-3-RR (same clone as 83392-3-PBS)

  WB result of GGTLC1 antibody (83392-3-RR; 1:1200; incubated at room temperature for 1.5 hours) with sh-Control and sh-GGTLC1 transfected HepG2 cells. This data was developed using the same antibody clone with 83392-3-PBS in a different storage buffer formulation.

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  WB analysis using 83392-3-RR (same clone as 83392-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83392-3-RR (GGTLC1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83392-3-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP00433-2

  Cytometric bead array standard curve of MP00433-2, GGTLC1 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 83392-2-PBS. Detection antibody: 83392-3-PBS. Standard: Ag11592. Range: 0.625-80 ng/mL.

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  Affinity and Kinetic Characterization of 83392-3-RR

  Biolayer interferometry (BLl) kinetic assays of 83392-3-RR against Human GGTLC1 were performed. The affinity constant is below 1 pM.

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Informations sur le produit

83392-3-PBS cible GGTLC1 dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: GGTLC1 Protéine recombinante Ag11592
• Nom complet: gamma-glutamyltransferase light chain 1
• Masse moléculaire calculée: 225 aa, 24 kDa
• Poids moléculaire observé: 20-24 kDa
• Numéro d’acquisition GenBank: BC040904
• Symbole du gène: GGTLC1
• Identification du gène (NCBI): 92086
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Gamma-glutamyltransferase light chain 1 (GGTLC1), initially named GGTL6, then GGTLA4, and later GGTLC1 in 2008, is a member of the gamma-glutamyl transferase (GGT) family. The most ubiquitously expressed human GGT gene, GGT1, encodes a single transmembrane polypeptide that is post-translationally processed to form a heavy and a light chain. Knockdown of GGTLC1 in Endometrial cancer (EC) cells was shown to induce G0/G1 phase arrest and apoptosis, underscoring the significance of GGTLC1 as a key regulator of these cellular processes in EC (PMID: 38841516).

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