Anticorps Polyclonal de lapin anti-GGTLC2

GGTLC2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 18191-1-PBS

Synonymes

Gamma-glutamyltransferase light chain 2, Gamma-glutamyltransferase-like protein 4, GGTL4, Glutathione hydrolase light chain 2

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Galerie de données de validation

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  WB analysis using 18191-1-AP (same clone as 18191-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 18191-1-AP (GGTLC2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18191-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 18191-1-AP (same clone as 18191-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 18191-1-AP (GGTLC2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18191-1-PBS in a different storage buffer formulation.

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Informations sur le produit

18191-1-PBS cible GGTLC2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: GGTLC2 Protéine recombinante Ag12911
• Nom complet: gamma-glutamyltransferase light chain 2
• Masse moléculaire calculée: 218 aa, 24 kDa
• Poids moléculaire observé: 24 kDa
• Numéro d’acquisition GenBank: BC069534
• Symbole du gène: GGTLC2
• Identification du gène (NCBI): 91227
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

GGT is a protease anchored to the cell membrane, consisting of a light chain and a heavy chain. GGTLC2 (Glutathione hydrolase light chain 2), also known as GGTL4, a constituent of the GGT family, has been characterized as an antioxidant gene, with emerging evidence indicating a potential link between its expression levels and sarcoma patient outcome (PMID: 40191433). Studies have shown that GGTLC2 is highly expressed in gastric cancer, promoting cell proliferation, invasion, and migration while inhibiting apoptosis and ferroptosis.

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