Anticorps Monoclonal anti-GIMAP5

GIMAP5 Monoclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1B6F2

N° de cat : 66943-1-PBS

Synonymes

1B6F2, hIAN5, HIMAP3, IAN 5, IAN4

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Galerie de données de validation

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  WB analysis of Jurkat using 66943-1-Ig (same clone as 66943-1-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 66943-1-Ig (GIMAP5 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66943-1-PBS in a different storage buffer formulation.

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  IHC staining of human lymphoma using 66943-1-Ig (same clone as 66943-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 66943-1-Ig (GIMAP5 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66943-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lymphoma using 66943-1-Ig (same clone as 66943-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 66943-1-Ig (GIMAP5 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66943-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66943-1-PBS cible GIMAP5 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: GIMAP5 Protéine recombinante Ag18045
• Nom complet: GTPase, IMAP family member 5
• Masse moléculaire calculée: 35 kDa
• Poids moléculaire observé: 30-35 kDa
• Numéro d’acquisition GenBank: BC011732
• Symbole du gène: GIMAP5
• Identification du gène (NCBI): 55340
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

GIMAP5 gene encodes immunity-associated nucleotide 5 protein (IAN5) belonging to GTPase immune-associated protein subfamily. GIMAP5 is widely expressed with high levels in lymph node and spleen. The loss of Gimap5 (GTPase of the 5) gene function is the underlying cause of lymphopenia and autoimmune diabetes in the BioBreeding (BB) rat. Mouse gimap5 is necessary for the survival of peripheral T cells, NK/NKT-cell development, hematopoietic progenitor cell survival and the maintenance of normal liver function. GIMAP5 may regulate T lymphocyte survival by mechanisms that operate upstream of mitochondria.

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