Anticorps Polyclonal de lapin anti-GINS1

GINS1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 16061-1-PBS

Synonymes

PSF1, KIAA0186, GINS complex subunit 1

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Galerie de données de validation

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  WB analysis using 16061-1-AP (same clone as 16061-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 16061-1-AP (GINS1 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16061-1-PBS in a different storage buffer formulation.

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  WB analysis using 16061-1-AP (same clone as 16061-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 16061-1-AP (GINS1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16061-1-PBS in a different storage buffer formulation.

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  IHC staining of human ovary cancer using 16061-1-AP (same clone as 16061-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue slide using 16061-1-AP (GINS1 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16061-1-PBS in a different storage buffer formulation.

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Informations sur le produit

16061-1-PBS cible GINS1 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: GINS1 Protéine recombinante Ag8895
• Nom complet: GINS complex subunit 1 (Psf1 homolog)
• Masse moléculaire calculée: 196 aa, 23 kDa
• Poids moléculaire observé: 20 kDa
• Numéro d’acquisition GenBank: BC012542
• Symbole du gène: GINS1
• Identification du gène (NCBI): 9837
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

GINS1, also known as Partner of SLD Five 1 (PSF1) is a member of the GINS (Go-Ichi-Nii-San) complex, which plays a vital role in the initiation and elongation of DNA replication (PMID: 34414190). GINS1 was initially found to be predominantly expressed in highly proliferating cells instead of mature cells. Later on, it was found that GINS was involved in the tumorigenesis of various cancers, including breast cancer, colorectal cancer, and hepatocellular carcinoma (PMID: 36065190).

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