Anticorps Recombinant de lapin anti-GINS1

GINS1 Recombinant Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

240234A2

N° de cat : 83293-1-RR

Synonymes

PSF1, KIAA0186, GINS complex subunit 1, 240234A2

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Galerie de données de validation

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  WB analysis using 83293-1-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 83293-1-RR (GINS1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

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  Affinity and Kinetic Characterization of 83293-1-RR

  Biolayer interferometry (BLl) kinetic assays of 83293-1-RR against Human GINS1 were performed. The affinity constant is below 1 pM.

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Applications testées

• Résultats positifs en WB: cellules Jurkat, cellules HeLa, cellules HepG2

Dilution recommandée

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

83293-1-RR cible GINS1 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: GINS1 Protéine recombinante Ag8895
• Nom complet: GINS complex subunit 1 (Psf1 homolog)
• Masse moléculaire calculée: 196 aa, 23 kDa
• Poids moléculaire observé: 20 kDa
• Numéro d’acquisition GenBank: BC012542
• Symbole du gène: GINS1
• Identification du gène (NCBI): 9837
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

GINS1, also known as Partner of SLD Five 1 (PSF1) is a member of the GINS (Go-Ichi-Nii-San) complex, which plays a vital role in the initiation and elongation of DNA replication (PMID: 34414190). GINS1 was initially found to be predominantly expressed in highly proliferating cells instead of mature cells. Later on, it was found that GINS was involved in the tumorigenesis of various cancers, including breast cancer, colorectal cancer, and hepatocellular carcinoma (PMID: 36065190).

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