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Anticorps Polyclonal de lapin anti-GIPC3-Specific

GIPC3-Specific Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 25479-1-PBS

Synonymes

Galerie de données de validation

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  • Western Blot (WB) analysis of various lysates using GIPC3-Specific Polyclonal antibody (25479-1-AP)

    WB analysis using 25479-1-AP (same clone as 25479-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 25479-1-AP (GIPC3-Specific antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25479-1-PBS in a different storage buffer formulation.

Informations sur le produit

25479-1-PBS cible GIPC3-Specific dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène Peptide
Nom complet GIPC PDZ domain containing family, member 3
Masse moléculaire calculée 34 kDa
Poids moléculaire observé40 kDa
Numéro d’acquisition GenBankNM_133261
Symbole du gène GIPC3
Identification du gène (NCBI) 126326
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Human PDZ domain-containing protein GIPC3 is a member of the GIPC (GAIP-interacting protein C-terminus) gene family, which is characterized by a single, conserved PDZ domain and GIPC homology (GH1 and GH2) domains. Aberrant expression of GIPC3 has been evidenced to correlate to the audiogenic seizures and sensorineural hearing loss in mouse and human (PMID: 36301034, 21326233). GIPC3 is upregulated in multiple cancer types, with a significant positive correlation of its expression with Hh signaling identified in melanoma cell lines (PMID: 34224745). This antibody is highly specific for GIPC3 protein.

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