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Anticorps Polyclonal de lapin anti-GLMN

GLMN Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32645-1-PBS

Synonymes

FAP, FAP48, FAP68, FK506-binding protein-associated protein, FKBP-associated protein

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using GLMN Polyclonal antibody (32645-1-AP)

    WB analysis using 32645-1-AP (same clone as 32645-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32645-1-AP (GLMN antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32645-1-PBS in a different storage buffer formulation.

Informations sur le produit

32645-1-PBS cible GLMN dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

Réactivité Humain, rat, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène GLMN Protéine recombinante Ag37763
Nom complet glomulin, FKBP associated protein
Masse moléculaire calculée 68 kDa
Poids moléculaire observé 68 kDa
Numéro d’acquisition GenBankBC001257
Symbole du gène GLMN
Identification du gène (NCBI) 11146
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Glomulin (GLMN) is a regulatory component of cullin-RING-based SCF (SKP1-Cullin-F-box protein) E3 ubiquitin-protein ligase complexes (PMID: 22405651; 22748924). It inhibits E3 ubiquitin ligase activity by binding to RBX1 (via the RING domain) and inhibiting its interaction with the E2 ubiquitin-conjugating enzyme CDC34 (PMID: 22405651; 22748924). GLMN is essential for normal vasculature development and contributes to the regulation of RPS6KB1 phosphorylation (PMID: 11845407; 11571281).

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