Anticorps Polyclonal de lapin anti-GLRX2

• Phare
• Validé par KD/KO

GLRX2 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 13381-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 13381-1-AP (same clone as 13381-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 13381-1-AP (GLRX2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13381-1-PBS in a different storage buffer formulation.

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  IF Staining of MCF-7 using 13381-1-AP (same clone as 13381-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed MCF-7 cells using GLRX2 antibody (13381-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 13381-1-PBS in a different storage buffer formulation.

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Informations sur le produit

13381-1-PBS cible GLRX2 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: GLRX2 Protéine recombinante Ag4218
• Nom complet: glutaredoxin 2
• Masse moléculaire calculée: 164 aa, 18 kDa
• Poids moléculaire observé: 16 kDa
• Numéro d’acquisition GenBank: BC028113
• Symbole du gène: GLRX2
• Identification du gène (NCBI): 51022
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

GLRX2(Glutaredoxin-2) is also named as GRX2 and belongs to the glutaredoxin family. It facilitates the maintenance of cellular redox homeostasis upon treatment with apoptotic agents, thereby preventing cardiolipin oxidation and cytochrome C release. The GLRX2, which exists in a dynamic equilibrium of enzymatically active monomers and quiescent dimers,is a 16-kDa protein directed either to the nucleus or to the mitochondria through differential splicing of the first exon(PMID: 17121859). It has 2 isoforms produced by alternative splicing.

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