Anticorps Recombinant de lapin anti-GLRX3

GLRX3 Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

251530F9

N° de cat : 86587-1-PBS

Synonymes

Glutaredoxin 3, GLRX4, Glutaredoxin-3, GRX3, GRX4

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Galerie de données de validation

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  WB analysis using 86587-1-RR (same clone as 86587-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86587-1-RR (GLRX3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86587-1-PBS in a different storage buffer formulation.

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  Cytometric bead array sample test of MP02531-1

  The mean GLRX3 concentration was determined to be 669.5 ng/mL in HEK-293 cell extract based on a 1.1 mg/mL extract load, 358.1 ng/mL in A549 cell extract based on a 1.2 mg/mL extract load.

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  Cytometric bead array standard curve of MP02531-1

  Cytometric bead array standard curve of MP02531-1, GLRX3 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 86587-1-PBS. Detection antibody: 86587-2-PBS. Standard: Ag1775. Range: 1.562-100 ng/mL.

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  Affinity and Kinetic Characterization of 86587-1-RR

  Biolayer interferometry (BLl) kinetic assays of 86587-1-RR against Human GLRX3 were performed. The affinity constant is 3.76 nM.

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Informations sur le produit

86587-1-PBS cible GLRX3 dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: GLRX3 Protéine recombinante Ag1775
• Nom complet: glutaredoxin 3
• Masse moléculaire calculée: 37 kDa
• Poids moléculaire observé: 37-40 kDa
• Numéro d’acquisition GenBank: BC014372
• Symbole du gène: GLRX3
• Identification du gène (NCBI): 10539
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

GLRX3(Glutaredoxin-3) is also named as PICOT, TXNL2. Mammalian glutaredoxin 3 is an essential protein involved in the regulation of signal transduction, for instance during immune cell activation and development of cardiac hypertrophy, presumably in response to redox signals(PMID:20226171). Glrx3 could take a pivotal role in colon and lung cancer cells during the tumorigenesis, which is expressed in lung and colon cancers consistently and preferentially(PMID:19797004).

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