Anticorps Recombinant de lapin anti-GM-CSF

GM-CSF Recombinant Antibody for FC (Intra)

Hôte / Isotype

Lapin / IgG

Réactivité testée

rat

Applications

FC (Intra)

Conjugaison

Non conjugué

CloneNo.

243117B1

N° de cat : 98463-3-PBS

Synonymes

Colony-stimulating factor, CSF, Csf2, Csfgm, Granulocyte-macrophage colony-stimulating factor

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Galerie de données de validation

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  FC experiment of Transfected HEK-293T using 98463-3-RR (same clone as 98463-3-PBS)

  1x10^6 HEK-293T cells or GM-CSF transfected HEK-293T cells were intracellularly stained with 0.25 ug Anti-Rat GM-CSF Rabbit RecAb (98463-3-RR, Clone: 243117B1) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and Multi-rAb CoraLite ® Plus 647-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR005). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98463-3-PBS in a different storage buffer formulation.

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  FC experiment of Transfected HEK-293T using 98463-3-RR (same clone as 98463-3-PBS)

  1x10^6 HEK-293T cells or GM-CSF transfected HEK-293T cells were intracellularly stained with 0.25 ug Anti-Rat GM-CSF/CSF2 Rabbit RecAb (98463-3-RR, Clone: 243117B1) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and Multi-rAb CoraLite ® Plus 647-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR005). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98463-3-PBS in a different storage buffer formulation.

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Informations sur le produit

98463-3-PBS cible GM-CSF dans les applications de FC (Intra) et montre une réactivité avec des échantillons rat

• Réactivité: rat
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: GM-CSF Protéine recombinante Eg3202
• Nom complet: colony stimulating factor 2 (granulocyte-macrophage)
• Masse moléculaire calculée: 17 kDa
• Numéro d’acquisition GenBank: NM_053852.1
• Symbole du gène: Csf2
• Identification du gène (NCBI): 116630
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

Gm-csf, also known as Csf2, is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts that functions as a cytokine. Gm-csf was first characterized as a hematopoietic growth factor that stimulates the proliferation of myeloid cells from bone-marrow progenitors. Gm-csf is now recognized as an important activating and differentiation factor for immune cells, and is essential for a wide range of biological processes in both innate and adaptive immunity. Gm-csf has been shown to protect against pulmonary infection and intestinal inflammation, and it is necessary for normal pulmonary and colon homeostasis.

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