Anticorps Polyclonal de lapin anti-GNA15

GNA15 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 12078-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 12078-1-AP (same clone as 12078-1-PBS)

  MOLT-4 cells were subjected to SDS PAGE followed by western blot with 12078-1-AP (GNA15 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12078-1-PBS in a different storage buffer formulation.

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  WB analysis using 12078-1-AP (same clone as 12078-1-PBS)

  mouse spleen tissue were subjected to SDS PAGE followed by western blot with 12078-1-AP (GNA15 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12078-1-PBS in a different storage buffer formulation.

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  IHC staining of human small intestine using 12078-1-AP (same clone as 12078-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 12078-1-AP (GNA15 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12078-1-PBS in a different storage buffer formulation.

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  IHC staining of human small intestine using 12078-1-AP (same clone as 12078-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 12078-1-AP (GNA15 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12078-1-PBS in a different storage buffer formulation.

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Informations sur le produit

12078-1-PBS cible GNA15 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: GNA15 Protéine recombinante Ag2738
• Nom complet: guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
• Masse moléculaire calculée: 374 aa, 44 kDa
• Poids moléculaire observé: 44 kDa
• Numéro d’acquisition GenBank: BC013585
• Symbole du gène: GNA15
• Identification du gène (NCBI): 2769
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

GNA15, also known as GNA16, belongs to the G-alpha family and G(q) subfamily. The protein encoded by the GNA15 gene is the alpha subunit of the G protein, which participates in the regulation of cell proliferation and apoptosis. GNA15 is highly expressed in some cell types, such as hematopoietic stem cells and epithelial cells during specific stages of differentiation. GNA15 is known to play as an oncogene in several tumors, such as gastroenteropancreatic neuroendocrine neoplasia (GEP-NEN), liver cancer, pancreatic ductal adenocarcinoma and ovarian cancer (PMID: 34552875). The molecular weight of GNA15 is 44 kDa.

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