Anticorps Monoclonal anti-GNAI3

GNAI3 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, rat, souris

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1A9B6

N° de cat : 68156-1-PBS

Synonymes

87U6, FLJ26559, G(i) alpha 3, GNAI3

---

Galerie de données de validation

• 

  WB analysis using 68156-1-Ig (same clone as 68156-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68156-1-Ig (GNAI3 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68156-1-PBS in a different storage buffer formulation.

• 

  IF Staining of HeLa using 68156-1-Ig (same clone as 68156-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed HeLa cells using GNAI3 antibody (68156-1-Ig, Clone: 1A9B6 ) at dilution of 1:800 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 68156-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

68156-1-PBS cible GNAI3 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: GNAI3 Protéine recombinante Ag32662
• Nom complet: guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
• Masse moléculaire calculée: 40 kDa
• Poids moléculaire observé: ~40 kDa
• Numéro d’acquisition GenBank: BC025285
• Symbole du gène: GNAI3
• Identification du gène (NCBI): 2773
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

GNAI3 is a member of the Gi group proteins, which belong to the Gα protein family. GNAI3 is involved in several critical biological processes and regulates many cellular activities, including proliferation, differentiation, apoptosis, and migration. For example, GNAI3 can regulate a class of K+ channels in response to hormone and neurotransmitter signals. In addition to its function as a downstream signal pathway switch for receptors on the plasma membrane, GNAI3 has also been shown to localize to the centrosome and affect cytokinesis. These indicate that GNAI3 has important receptor-independent functions. The molecular weight of GNAI3 is 40 kDa. (PMID: 25444921, 34803495)

{{ptg:RelatedPrimaryAntibodies}}