Anticorps Monoclonal anti-GNE

GNE Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, rat

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2A11E10

N° de cat : 67649-1-PBS

Synonymes

2A11E10, Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, GLCNE, hydrolyzing, IBM2

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Galerie de données de validation

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  WB analysis using 67649-1-Ig (same clone as 67649-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67649-1-Ig (GNE antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67649-1-PBS in a different storage buffer formulation.

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Informations sur le produit

67649-1-PBS cible GNE dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: GNE Protéine recombinante Ag18702
• Nom complet: glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
• Masse moléculaire calculée: 722 aa, 79 kDa
• Poids moléculaire observé: 79 kDa
• Numéro d’acquisition GenBank: BC121179
• Symbole du gène: GNE
• Identification du gène (NCBI): 10020
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The bifunctional enzyme UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase (GNE) is essential for early embryonic development and catalyzes the rate limiting step in sialic acid biosynthesis. It plays an important role in neuronal cell and brain development, and is strongly involved in cardiac tissue and skeletal muscle early survival and organization.. This protein has 5 isoforms produced by alternative splicing.

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