Anticorps Polyclonal de lapin anti-GNG7

GNG7 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31393-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 31393-1-AP (same clone as 31393-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31393-1-AP (GNG7 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31393-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31393-1-PBS cible GNG7 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons rat, souris

• Réactivité: rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: GNG7 Protéine recombinante Ag34754
• Nom complet: guanine nucleotide binding protein (G protein), gamma 7
• Masse moléculaire calculée: 8 kDa
• Poids moléculaire observé: 10 kDa
• Numéro d’acquisition GenBank: BC014466
• Symbole du gène: GNG7
• Identification du gène (NCBI): 2788
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

GNG7 belongs to the large guanine nucleotide binding protein γ family and is located on chromosome 19. Related genes of the G protein family are involved in various transmembrane signaling transduction pathways. GNG7 may be associated with transmembrane signaling pathways and involved in cell contact-induced growth arrest, thus repressing uncontrolled cell proliferation in multicellular organisms. GNG7 is a heterotrimeric G protein subunit with ubiquitous expression in various tissues but low expression in cancer. GNG7 overexpression inhibited cell growth and tumorigenicity of esophageal carcinoma cells. Also, GNG7 was confirmed as an essential autophagy-inducing agent and participated in inhibiting tumor progression through mTOR pathway (PMID: 30864685, 35281820, 36159963).

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