Anticorps Polyclonal de lapin anti-GNL2

GNL2 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 10190-2-PBS

Synonymes

Autoantigen NGP 1, Autoantigen NGP-1, HUMAUANTIG, Ngp 1, NGP1

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Galerie de données de validation

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  WB analysis using 10190-2-AP (same clone as 10190-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 10190-2-AP (GNL2 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10190-2-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 10190-2-AP (same clone as 10190-2-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer using 10190-2-AP (GNL2 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 10190-2-PBS in a different storage buffer formulation.

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  IF Staining of A431 using 10190-2-AP (same clone as 10190-2-PBS)

  Immunofluorescent analysis of (4% PFA) fixed A431 cells using GNL2 antibody (10190-2-AP) at dilution of 1:1000 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 10190-2-PBS in a different storage buffer formulation.

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Informations sur le produit

10190-2-PBS cible GNL2 dans les applications de WB, IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: GNL2 Protéine recombinante Ag0243
• Nom complet: guanine nucleotide binding protein-like 2 (nucleolar)
• Masse moléculaire calculée: 731 aa, 84 kDa
• Poids moléculaire observé: 100 kDa
• Numéro d’acquisition GenBank: BC000107
• Symbole du gène: GNL2
• Identification du gène (NCBI): 29889
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

GNL2 ( G protein nucleolar 2) has a crucial role in the pathogenesis of gliomas by influencing key cellular processes, particularly enhanced protein synthesis, which ultimately contributes to the development of gliomas. In addition, GNL2 was found to affect the overall protein synthesis of ribosomal protein L11 in glioma cells. The calculated MW of GNL2 is 84 kDa, but the observed MW is around 100 kDa, which may be due to glycosylation modification.

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