Anticorps Recombinant de lapin anti-GNRHR

GNRHR Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

7E11

N° de cat : 82847-1-PBS

Synonymes

GnRH R, GnRH receptor, GNRHR, GNRHR1, GRHR, LHRHR, LRHR

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Galerie de données de validation

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  WB analysis using 82847-1-RR (same clone as 82847-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 82847-1-RR (GNRHR antibody) at dilution of 1:5100 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82847-1-PBS in a different storage buffer formulation.

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Informations sur le produit

82847-1-PBS cible GNRHR dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: GnRH receptor
• Masse moléculaire calculée: 38 kDa
• Poids moléculaire observé: ~38 kDa
• Numéro d’acquisition GenBank: NM_000406
• Symbole du gène: GNRHR
• Identification du gène (NCBI): 2798
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

GNRHR, also named GRHR, belongs to the G-protein coupled receptor 1 family. GNRHR is a receptor for GnRH that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). It mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform2 of GNRHR may act as an inhibitor of GnRH-R signaling. Defects in GNRHR are a cause of idiopathic hypogonadotropic hypogonadism (IHH). Defects in GNRHR are a cause of fertile eunuch syndrome. The predicted unmodified molecular weight of the human GNRHR is ~38 kDa, the larger band (50-65 kDa) is likely to represent a glycosylated form of GNRHR.

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