Anticorps Monoclonal anti-GOT2

GOT2 Monoclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, porc, poulet, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1B6C6

N° de cat : 67738-1-PBS

Synonymes

FABP 1, FABPpm, Fatty acid binding protein, FLJ40994, GOT2, KAT4, KATIV, mAspAT, mitAAT, Transaminase A

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Galerie de données de validation

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  WB analysis using 67738-1-Ig (same clone as 67738-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67738-1-Ig (GOT2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67738-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 67738-1-Ig (same clone as 67738-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67738-1-Ig (GOT2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67738-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse heart using 67738-1-Ig (same clone as 67738-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 67738-1-Ig (GOT2 antibody) at dilution of 1:8000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67738-1-PBS in a different storage buffer formulation.

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  IHC staining of rat heart using 67738-1-Ig (same clone as 67738-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat heart tissue slide using 67738-1-Ig (GOT2 antibody) at dilution of 1:8000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67738-1-PBS in a different storage buffer formulation.

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  IHC staining of rat brain using 67738-1-Ig (same clone as 67738-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 67738-1-Ig (GOT2 antibody) at dilution of 1:8000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67738-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat heart using 67738-1-Ig (same clone as 67738-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat heart tissue slide using 67738-1-Ig (GOT2 antibody) at dilution of 1:8000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67738-1-PBS in a different storage buffer formulation.

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Informations sur le produit

67738-1-PBS cible GOT2 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, porc, poulet, rat, souris

• Réactivité: Humain, porc, poulet, rat, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: GOT2 Protéine recombinante Ag6600
• Nom complet: glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)
• Masse moléculaire calculée: 47 kDa
• Poids moléculaire observé: 39-40 kDa
• Numéro d’acquisition GenBank: BC000525
• Symbole du gène: GOT2
• Identification du gène (NCBI): 2806
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

GOT2 encodes the mitochondrial glutamate oxaloacetate transaminase and plays an essential role in the intracellular NAD(H) redox balance. Upregulation of GOT2 has been reported in various cancers, including breast cancer and pancreatic cancer. GOT2 mutation leads to autosomal recessive neurometabolic disorder.

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