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Anticorps Recombinant de lapin anti-GPC1

GPC1 Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

240207G5

N° de cat : 83318-4-PBS

Synonymes

glypican 1, 240207G5, FLJ38078, glypican, glypican1

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of HepG2 cells using GPC1 Recombinant antibody (83318-4-RR)

    WB analysis of HepG2 using 83318-4-RR (same clone as 83318-4-PBS)

    HepG2 cells were subjected to SDS PAGE followed by western blot with 83318-4-RR (GPC1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83318-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83318-4-RR

    Affinity and Kinetic Characterization of 83318-4-RR

    Biolayer interferometry (BLl) kinetic assays of 83318-4-RR against Human GPC1 were performed. The affinity constant is 3.58 nM.

Informations sur le produit

83318-4-PBS cible GPC1 dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène GPC1 Protéine recombinante Eg0737
Nom complet glypican 1
Masse moléculaire calculée 558 aa, 62 kDa
Poids moléculaire observé 61-65 kDa
Numéro d’acquisition GenBankBC051279
Symbole du gène GPC1
Identification du gène (NCBI) 2817
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine A
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Glypicans are a family of HSPGs that are attached to the cell membrane by a glycosyl-phosphatidylinositol anchor. Glypicans are considered to have the ability to modulate the activities of HBGFs. The expression of glypicans is regulated temporally and spatially during development, suggesting they are involved in development and morphogenesis. To date, six glypicans (GPC1 to GPC6) have been identified in mammals. GPC1 is most ubiquitously expressed in adult tissues. GPC1 promotes efficient signaling by HBGFs and plays a critical role in cell growth and differentiation. GPC1 is involved in tumorigenesis and angiogenesis, and is frequently overexpressed in several types of tumors including pancreatic carcinoma, breast cancer and glioma.

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