Anticorps Recombinant de lapin anti-GPR126

GPR126 Recombinant Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

6M2

N° de cat : 81632-1-PBS

Synonymes

APG1, DREG, G protein coupled receptor 126, GPR126, PS1TP2, VIGR

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Galerie de données de validation

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  IHC staining of mouse kidney using 81632-1-RR (same clone as 81632-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 81632-1-RR (GPR126 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 81632-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 81632-1-RR (same clone as 81632-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 81632-1-RR (GPR126 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 81632-1-PBS in a different storage buffer formulation.

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Informations sur le produit

81632-1-PBS cible GPR126 dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: GPR126 Protéine recombinante Ag12195
• Nom complet: G protein-coupled receptor 126
• Masse moléculaire calculée: 1222 aa, 137 kDa
• Numéro d’acquisition GenBank: BC075798
• Symbole du gène: GPR126
• Identification du gène (NCBI): 57211
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

GPR126 (G protein-coupled receptor 126) is a member of the adhesion GPCR family. GPR126 is all widely expressed on stromal cells (PMID: 25713288). It is essential for normal differentiation of promyelinating Schwann cells and for normal myelination of axons (PMID: 24227709). GPR126 regulates neural, cardiac and ear development by G-protein- and/or N-terminus-dependent signaling (PMID: 24082093, PMID: 24067352). GPR126 also stimulates VEGF signaling and angiogenesis by modulating VEGF receptor 2 expression through STAT5 and GATA2 in endothelial cells.

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