Anticorps Polyclonal de lapin anti-GPR137

• Phare
• Validé par KD/KO

GPR137 Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 11929-1-PBS

Synonymes

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Galerie de données de validation

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  IHC staining of human gliomas using 11929-1-AP (same clone as 11929-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas using 11929-1-AP (GPR137 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11929-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11929-1-AP (GPR137 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11929-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11929-1-AP (GPR137 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11929-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11929-1-AP (GPR137 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11929-1-PBS in a different storage buffer formulation.

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Informations sur le produit

11929-1-PBS cible GPR137 dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: GPR137 Protéine recombinante Ag2611
• Nom complet: G protein-coupled receptor 137
• Masse moléculaire calculée: 396 aa, 44 kDa
• Numéro d’acquisition GenBank: BC033920
• Symbole du gène: GPR137
• Identification du gène (NCBI): 56834
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

G protein-coupled receptors (GPRs) are highly related to oncogenesis and cancer metastasis. G protein-coupled receptor 137 (GPR137) was initially reported as a novel orphan GPR about 10 years ago. GPR137 is ubiquitously expressed in the central nervous system (CNS), mainly in the hippocampus (PMID: 22025619). GPR137 is involved in the progression of human glioma, suggesting GPR137 as a potential oncogene of glioma cells (PMID: 24870220). Recent study shows that GPR137 plays an important role in colon cancer cell proliferation (PMID: 25301753).

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