Anticorps Polyclonal de lapin anti-GPR155

GPR155 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 12659-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 12659-1-AP (same clone as 12659-1-PBS)

  mouse brain lysates were subjected to SDS PAGE followed by western blot with 12659-1-AP (GPR155 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12659-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse brain using 12659-1-AP (same clone as 12659-1-PBS)

  IP result of anti-GPR155 (IP:12659-1-AP, 4ug; Detection:12659-1-AP 1:300) with mouse brain tissue lysate 3000ug. This data was developed using the same antibody clone with 12659-1-PBS in a different storage buffer formulation.

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  IHC staining of human brain using 12659-1-AP (same clone as 12659-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 12659-1-AP (GPR155 Antibody) at dilution of 1:100 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12659-1-PBS in a different storage buffer formulation.

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  IHC staining of human brain using 12659-1-AP (same clone as 12659-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 12659-1-AP (GPR155 Antibody) at dilution of 1:100 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12659-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 12659-1-AP (same clone as 12659-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 12659-1-AP (GPR155 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12659-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 12659-1-AP (same clone as 12659-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 12659-1-AP (GPR155 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12659-1-PBS in a different storage buffer formulation.

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Informations sur le produit

12659-1-PBS cible GPR155 dans les applications de WB, IHC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: GPR155 Protéine recombinante Ag3328
• Nom complet: G protein-coupled receptor 155
• Masse moléculaire calculée: 870 aa, 97 kDa
• Poids moléculaire observé: 97 kDa, 75 kDa
• Numéro d’acquisition GenBank: BC028730
• Symbole du gène: GPR155
• Identification du gène (NCBI): 151556
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The G Protein-coupled receptor 155 (GPR155), also known as Lysosomal cholesterol signaling protein (LYCHOS), is a cholesterol receptor on the lysosome. GRR155 plays a role in the cholesterol-sensing lysosomal pathway and couples cholesterol concentration to MTORC1-dependent anabolic signaling (PMID: 36007018). GPR155 may represent a biomarker for diagnosing and predicting hematogenous metastasis of gastric cancer (PMID: 28165032).

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