Anticorps Recombinant de lapin anti-GPR17

GPR17 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250471E11

N° de cat : 86089-1-PBS

Synonymes

G protein coupled receptor 17, G-protein coupled receptor 17, P2Y like receptor, P2Y-like receptor, R12

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Galerie de données de validation

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  WB analysis using 86089-1-RR (same clone as 86089-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 86089-1-RR (GPR17 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86089-1-PBS in a different storage buffer formulation.

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Informations sur le produit

86089-1-PBS cible GPR17 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: GPR17 Protéine recombinante Ag4106
• Nom complet: G protein-coupled receptor 17
• Masse moléculaire calculée: 367 aa, 41 kDa
• Poids moléculaire observé: 48 kDa
• Numéro d’acquisition GenBank: BC031653
• Symbole du gène: GPR17
• Identification du gène (NCBI): 2840
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

GPR17 is a G protein-coupled receptor (GPCR) that plays a significant role in various physiological processes, particularly in the central nervous system (CNS). GPR17 is considered a modulator of CNS myelination and is involved in reconstructing and repairing demyelinating plaques caused by ongoing inflammatory processes, such as in multiple sclerosis (MS). It is present in nerve cells and precursor oligodendrocyte cells, playing a role in the differentiation and maturation of oligodendrocytes (PMID: 32182666). GPR17 is a multifaceted GPCR with implications in immune regulation, glucose metabolism, neurodegenerative diseases, and potentially in treating anxiety disorders.

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