Anticorps Polyclonal de lapin anti-GPR175

GPR175 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 33499-1-PBS

Synonymes

Integral membrane protein GPR175, PP6566, TMEM227, TPRA1, TPRA40

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Galerie de données de validation

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  WB analysis using 33499-1-AP (same clone as 33499-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 33499-1-AP (GPR175 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33499-1-PBS in a different storage buffer formulation.

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  WB analysis using 33499-1-AP (same clone as 33499-1-PBS)

  Human placenta tissue were subjected to SDS PAGE followed by western blot with 33499-1-AP (GPR175 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33499-1-PBS in a different storage buffer formulation.

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Informations sur le produit

33499-1-PBS cible GPR175 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: GPR175 Protéine recombinante Ag39379
• Nom complet: G protein-coupled receptor 175
• Poids moléculaire observé: 55 kDa
• Numéro d’acquisition GenBank: BC050711
• Symbole du gène: GPR175
• Identification du gène (NCBI): 131601
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

GPR175, also known as TPRA1 or TPRA40, is a transmembrane protein. GPR175 was first cloned as a GLP-1 receptor homolog in 3T3-L1 adipocytes and is also expressed in tissues that require Hh signaling during development, including the heart, brain, lung, pancreas, and muscle. Endogenous GPR175 localizes to cilia in a Hh-dependent manner, where it can interact with (constitutively) ciliary Gαi1 to inhibit the local production of cAMP by adenylyl cyclase. The calculated molecular weight of GPR175 is 41 kDa. With glycosylation modification, the molecular weight of GPR175 will be migrated to 55 kDa. (PMID: 26451044)

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