Anticorps Polyclonal de lapin anti-GPR179

GPR179 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 29934-1-PBS

Synonymes

GPR158L1, G protein coupled receptor 179

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Galerie de données de validation

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  WB analysis using 29934-1-AP (same clone as 29934-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 29934-1-AP (GPR179 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29934-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse liver using 29934-1-AP (same clone as 29934-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 29934-1-AP (GPR179 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29934-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse liver using 29934-1-AP (same clone as 29934-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 29934-1-AP (GPR179 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29934-1-PBS in a different storage buffer formulation.

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Informations sur le produit

29934-1-PBS cible GPR179 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: GPR179 Protéine recombinante Ag32180
• Nom complet: G protein-coupled receptor 179
• Masse moléculaire calculée: 257 kDa
• Poids moléculaire observé: 260-270 kDa
• Numéro d’acquisition GenBank: NM_001004334.3
• Symbole du gène: GPR179
• Identification du gène (NCBI): 440435
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

GPR179 (Probable G-protein coupled receptor 179) belongs to the glutamate receptor subfamily of GPCRs, which is involved in signal transduction through retinal depolarizing bipolar cells. The protein has an EGF-like calcium binding domain and a seven transmembrane domain in the N-terminal region of the protein. Mutations in this gene are associated with congenital stationary night blindness type 1E. GPR179 is expressed in retinal bipolar cells and upregulated in rd1 mice retina with Pde6b mutations (PubMed: 22325361, PubMed: 22325362).

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