Anticorps Polyclonal de lapin anti-GPR4

GPR4 Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 28232-1-PBS

Synonymes

G protein coupled receptor 4, G-protein coupled receptor 4, G-protein coupled receptor 6C.l

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Galerie de données de validation

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  IHC staining of mouse lung using 28232-1-AP (same clone as 28232-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse lung tissue slide using 28232-1-AP (GPR4 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28232-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 28232-1-AP (same clone as 28232-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 28232-1-AP (GPR4 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28232-1-PBS in a different storage buffer formulation.

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Informations sur le produit

28232-1-PBS cible GPR4 dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: GPR4 Protéine recombinante Ag28273
• Nom complet: G protein-coupled receptor 4
• Masse moléculaire calculée: 362 aa, 41 kDa
• Numéro d’acquisition GenBank: BC067535
• Symbole du gène: GPR4
• Identification du gène (NCBI): 2828
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

GPR4 (G-protein-coupled receptor 4) is a proton-sensing G-protein-coupled receptor (GPCR) that contributes to neovascularization in acidic microenvironments (PMID: 33632325). GPR4 is highly expressed in vascular endothelial cells (ECs) and blood vessel-rich tissues such as the lung, kidney, heart, and liver. Moreover, GPR4 has been shown to mediate EC inflammatory responses to acidosis and is central for leukocyte-endothelium interaction (PMID: 27940273).

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