Anticorps Polyclonal de lapin anti-GPR87

GPR87 Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 25999-1-PBS

Synonymes

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Galerie de données de validation

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  IHC staining of mouse bladder using 25999-1-AP (same clone as 25999-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse bladder tissue slide using 25999-1-AP (GPR87 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25999-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse bladder using 25999-1-AP (same clone as 25999-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse bladder tissue slide using 25999-1-AP (GPR87 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25999-1-PBS in a different storage buffer formulation.

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Informations sur le produit

25999-1-PBS cible GPR87 dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: GPR87 Protéine recombinante Ag23214
• Nom complet: G protein-coupled receptor 87
• Numéro d’acquisition GenBank: BC132888
• Symbole du gène: GPR87
• Identification du gène (NCBI): 53836
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

G Protein-Coupled Receptor 87 (GPR87) is a GPCR, and it has been demonstrated to regulate the progression of several tumors (PMID:18183596). Studied reported that GPR87 promotes PDA (Pancreatic ductal adenocarcinoma) proliferation, angiogenesis, gemcitabine resistance, and tumorigenicity through activating the nuclear factor-kB (NF-kB) pathway (PMID:32405536). GPR87 is an independent prognostic factor for bladder cancer intravesical recurrence; it promotes bladder cancer cell proliferation and inhibits apoptosis. In addition, GPR87 was deorphanized and shown to be a lysophosphatidic acid (LPA) receptor (PMID:23752273).

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