Anticorps Polyclonal de lapin anti-Glutamate receptor 3/GluA3

Glutamate receptor 3/GluA3 Polyclonal Antibody for WB, IF-P, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IF-P, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 29588-1-PBS

Synonymes

GRIA3, GLURC, GLUR3, GLUR K3, GLUR C

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Galerie de données de validation

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  WB analysis using 29588-1-AP (same clone as 29588-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29588-1-AP (Glutamate receptor 3/GluA3 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29588-1-PBS in a different storage buffer formulation.

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  WB analysis using 29588-1-AP (same clone as 29588-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29588-1-AP (GRIA3 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29588-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse brain using 29588-1-AP (same clone as 29588-1-PBS)

  IP result of anti-GRIA3 (IP:29588-1-AP, 4ug; Detection:29588-1-AP 1:1000) with mouse brain tissue lysate 1280 ug. This data was developed using the same antibody clone with 29588-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse brain using 29588-1-AP (same clone as 29588-1-PBS)

  IP result of anti-Glutamate receptor 3/GluA3 (IP:29588-1-AP, 4ug; Detection:29588-1-AP 1:2000) with mouse brain tissue lysate 1280 ug. This data was developed using the same antibody clone with 29588-1-PBS in a different storage buffer formulation.

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  IF Staining of mouse brain using 29588-1-AP (same clone as 29588-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse brain tissue using Glutamate receptor 3/GluA3 antibody (29588-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29588-1-PBS in a different storage buffer formulation.

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  IF Staining of rat brain using 29588-1-AP (same clone as 29588-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded rat brain tissue using Glutamate receptor 3/GluA3 antibody (29588-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29588-1-PBS in a different storage buffer formulation.

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Informations sur le produit

29588-1-PBS cible Glutamate receptor 3/GluA3 dans les applications de WB, IF-P, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Glutamate receptor 3/GluA3 Protéine recombinante Ag30898
• Nom complet: glutamate receptor, ionotrophic, AMPA 3
• Masse moléculaire calculée: 101 kDa
• Poids moléculaire observé: 101 kDa
• Numéro d’acquisition GenBank: NM_007325
• Symbole du gène: GRIA3
• Identification du gène (NCBI): 2892
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. GRIA3 (Glutamate ionotropic receptor AMPA type subunit 3), also known as Glutamate receptor R3 or A3 (GluR3 or GluA3), is associated with X-linked intellectual disability (ID), dysmorphic features, and non-syndromic epilepsy(PMID: 32977175). GRIA3 also plays a role as a mediator of tumor progression in pancreatic cancer downstream CUX1(PMID: 20689760).

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