Anticorps Polyclonal de lapin anti-GRINA

GRINA Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 20851-1-PBS

Synonymes

Glutamate [NMDA] receptor-associated protein 1, HNRGW, LFG1, Protein lifeguard 1, Putative MAPK-activating protein PM02

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Galerie de données de validation

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  WB analysis using 20851-1-AP (same clone as 20851-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 20851-1-AP (GRINA antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20851-1-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 20851-1-AP (same clone as 20851-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 20851-1-AP (GRINA antibody) at dilution of 1:600 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20851-1-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 20851-1-AP (same clone as 20851-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 20851-1-AP (GRINA antibody) at dilution of 1:600 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20851-1-PBS in a different storage buffer formulation.

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Informations sur le produit

20851-1-PBS cible GRINA dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: GRINA Protéine recombinante Ag14716
• Nom complet: glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
• Masse moléculaire calculée: 371 aa, 41 kDa
• Poids moléculaire observé: 49 kDa
• Numéro d’acquisition GenBank: BC041788
• Symbole du gène: GRINA
• Identification du gène (NCBI): 2907
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Glutamate Receptor Ionotropic NMDA-Associated Protein 1 (GRINA, also known as TMBIM3) is a transmembrane protein involved in calcium homeostasis and cell survival. It plays a crucial role in regulating intracellular calcium levels, which are essential for processes such as cell survival, neurotransmitter release, and apoptosis (PMID: 32124700). GRINA also involves vesicle transport and sorting, particularly in secretory cells like neurons and mammary glands (PMID: 31426446). Additionally, GRINA has been implicated in regulating aerobic glycolysis and tumor progression in gastric cancer (PMID: 30541591).

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