Anticorps Polyclonal de lapin anti-GRK5

• Phare
• Validé par KD/KO

GRK5 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17032-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of human skeletal muscle using 17032-1-AP (same clone as 17032-1-PBS)

  human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 17032-1-AP (GRK5 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17032-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 17032-1-AP (same clone as 17032-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17032-1-AP (GRK5 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17032-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 17032-1-AP (same clone as 17032-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17032-1-AP (GRK5 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17032-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human skeletal muscle using 17032-1-AP (same clone as 17032-1-PBS)

  human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 17032-1-AP (GRK5 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17032-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skeletal muscle using 17032-1-AP (same clone as 17032-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue slide using 17032-1-AP (GRK5 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 17032-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skeletal muscle using 17032-1-AP (same clone as 17032-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue slide using 17032-1-AP (GRK5 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 17032-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse heart using 17032-1-AP (same clone as 17032-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 17032-1-AP (GRK5 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17032-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse heart using 17032-1-AP (same clone as 17032-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 17032-1-AP (GRK5 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17032-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17032-1-PBS cible GRK5 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: GRK5 Protéine recombinante Ag10511
• Nom complet: G protein-coupled receptor kinase 5
• Masse moléculaire calculée: 590 aa, 68 kDa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: BC064506
• Symbole du gène: GRK5
• Identification du gène (NCBI): 2869
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

GRK5, also named as GPRK5, belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family and GPRK subfamily. It is Serine/threonine kinase that phosphorylates preferentially the activated forms of a variety of G-protein-coupled receptors (GPCRs). Phosphorylation of ARRB1 by GRK5 inhibits G-protein independent MAPK1/MAPK3 signaling downstream of 5HT4-receptors. GRK5 is crucial for proper neuronal morphogenesis and the establishment of functional neuronal circuitry.

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