• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

Anticorps Polyclonal de lapin anti-ProGRP

ProGRP Polyclonal Antibody for ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain et plus (1)

Applications

IHC,ELISA

Conjugaison

Non conjugué

N° de cat : 14646-1-AP

Synonymes

BN, gastrin releasing peptide, GRP, GRP 10, preproGRP, proGRP

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of Transfected HEK-293 cells using ProGRP Polyclonal antibody (14646-1-AP)

    WB analysis of Transfected HEK-293 using 14646-1-AP

    Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 14646-1-AP (ProGRP antibody at dilution of 1:500 incubated at room temperature for 1.5 hours.

Applications testées

Dilution recommandée

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Applications publiées

IHCSee 1 publications below

Informations sur le produit

14646-1-AP cible ProGRP dans les applications de IHC,ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Réactivité citéeChimpanzé
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène ProGRP Protéine recombinante Ag6239
Nom complet gastrin-releasing peptide
Masse moléculaire calculée 16 kDa
Numéro d’acquisition GenBankBC004488
Symbole du gène GRP
Identification du gène (NCBI) 2922
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
Conditions de stockageStocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Gastrin-releasing peptide, also known as GRP, is normally formed by mucosal cells in the gastric antrum and by the D cells of the pancreatic islets, and its main function is to stimulate secretion of HCl by the gastric mucosa. HCl, in turn, inhibits gastrin formation. Its 148-amino acid preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27-amino acid gastrin-releasing peptide or the 10-amino acid neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation.These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate.

Publications

SpeciesApplicationTitle
chimpanzeeIHC

Brain Struct Funct

The von Economo neurons in frontoinsular and anterior cingulate cortex in great apes and humans.

Authors - Allman John M JM
View Article