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Anticorps Recombinant de lapin anti-GSDMA

GSDMA Recombinant Antibody for Indirect ELISA, WB

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

Indirect ELISA, WB

Conjugaison

Non conjugué

CloneNo.

230161D4

N° de cat : 82920-1-PBS

Synonymes

Gasdermin-A, Gasdermin-1, gasdermin A, Gasdermin 1, FKSG9

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of Daudi cells using GSDMA Recombinant antibody (82920-1-RR)

    WB analysis of Daudi using 82920-1-RR (same clone as 82920-1-PBS)

    Daudi cells were subjected to SDS PAGE followed by western blot with 82920-1-RR (GSDMA antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82920-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 82920-1-RR

    Affinity and Kinetic Characterization of 82920-1-RR

    Biolayer interferometry (BLl) kinetic assays of 82920-1-RR against Human GSDMA were performed. The affinity constant is below 1 pM.

Informations sur le produit

82920-1-PBS cible GSDMA dans les applications de Indirect ELISA, WB et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène GSDMA Protéine recombinante Ag24407
Nom complet gasdermin A
Masse moléculaire calculée 445 aa, 49 kDa
Poids moléculaire observé49 kDa
Numéro d’acquisition GenBankBC109197
Symbole du gène GSDMA
Identification du gène (NCBI) 284110
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine A
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Gasdermins, a family of five pore-forming proteins (GSDMA-GSDME) in humans expressed predominantly in the skin, mucosa and immune sentinel cells, are key executioners of inflammatory cell death (pyroptosis), which recruits immune cells to infection sites and promotes protective immunity. GSDMA was predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity, phosphatidylinositol-4-phosphate binding activity, and phosphatidylserine binding activity. Involved in apoptotic process.

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