Anticorps Polyclonal de lapin anti-GSDMC

GSDMC Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 30469-1-PBS

Synonymes

---

Galerie de données de validation

• 

  WB analysis using 30469-1-AP (same clone as 30469-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 30469-1-AP (GSDMC antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30469-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 30469-1-AP (same clone as 30469-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 30469-1-AP (GSDMC antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30469-1-PBS in a different storage buffer formulation.

• 

  IHC staining of Human bowens disease using 30469-1-AP (same clone as 30469-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brown disease slide using 30469-1-AP (GSDMC antibody) at dilution of 1:600 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30469-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

30469-1-PBS cible GSDMC dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: GSDMC Protéine recombinante Ag33319
• Nom complet: gasdermin C
• Masse moléculaire calculée: 58kd
• Poids moléculaire observé: 58 kDa
• Numéro d’acquisition GenBank: NM_031415
• Symbole du gène: GSDMC
• Identification du gène (NCBI): 56169
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Gasdermin (GSDM) superfamily consists of Gasdermin family genes (GSDMA, GSDMB, GSDMC and GSDMD in humans) and Gasdermin-related genes (DFNA5, DFNB59 in humans). GSDM family members were shown to be detected in the epithelium of various tissue types in a highly tissue-specific manner and suggested to have differentiation-status specific roles. Gasdermin C (GSDMC) was known as melanoma-derived leucine zipper-containing extranuclear factor (MLZE). Several studies have suggested that GSDMC may be involved in the course of tumorigenesis such as acquisition of metastatic potential in melanoma cells or promotion of cell proliferation in colorectal carcinogenesis and that GSDMC may function as an oncogene. (PMID: 29428815)

{{ptg:RelatedPrimaryAntibodies}}