Anticorps Recombinant de lapin anti-GSTP1

GSTP1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

251705C10

N° de cat : 86708-1-PBS

Synonymes

EC:2.5.1.18, FAEES3, Glutathione S-transferase P, GST3, GST3/GST pi

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Galerie de données de validation

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  WB analysis using 86708-1-RR (same clone as 86708-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86708-1-RR (GSTP1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86708-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 86708-1-RR

  Biolayer interferometry (BLl) kinetic assays of 86708-1-RR against Human GSTP1 were performed. The affinity constant is 5.60 nM.

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Informations sur le produit

86708-1-PBS cible GSTP1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: GSTP1 Protéine recombinante Ag8731
• Nom complet: glutathione S-transferase pi 1
• Masse moléculaire calculée: 210 aa, 23 kDa
• Poids moléculaire observé: 23~28 kDa
• Numéro d’acquisition GenBank: BC010915
• Symbole du gène: GSTP1
• Identification du gène (NCBI): 2950
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Glutathione S-transferase Pi (GSTP1) is anisozyme encoded by the GST pi gene that plays an importantregulatory role in detoxification, anti‑oxidative damage, and the occurrence of various diseases (PMID: 14755684). GSTP1 conjugates reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. It is involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) (PMID:9084911). GSTP1 methylation is frequently associated with tumor development or poor prognosis in a wide range of tumors such as neuroblastoma, hepatocellular carcinoma, endometrial, breast, and prostate cancers (PCa) (PMID: 27594734).

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