Anticorps Polyclonal de lapin anti-GTPBP10

GTPBP10 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32944-1-PBS

Synonymes

GTP-binding protein 10, ObgH2, Protein obg homolog 2, UG0751c10

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Galerie de données de validation

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  WB analysis using 32944-1-AP (same clone as 32944-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32944-1-AP (GTPBP10 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32944-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32944-1-PBS cible GTPBP10 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: GTPBP10 Protéine recombinante Ag37974
• Nom complet: GTP-binding protein 10 (putative)
• Masse moléculaire calculée: 43, 34, 12 kDa
• Poids moléculaire observé: 42, 34, 20 kDa
• Numéro d’acquisition GenBank: BC107714
• Symbole du gène: GTPBP10
• Identification du gène (NCBI): 85865
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

GTPBP10, a member of the conserved Obg family of P-loop small G proteins, is a mitochondrial protein. The absence of GTPBP10 leads to attenuated mtLSU and mtSSU levels and the virtual absence of the 55S monosome, which entirely prevents mitochondrial protein synthesis. GTPBP10 physically interacts with the 16S rRNA, but not with the 12S rRNA, and crosslinks with several mtLSU proteins. Additionally, GTPBP10 is indirectly required for efficient processing of the 12S-16S rRNA precursor transcript, which could explain the mtSSU accumulation defect (PMID: 30321378).

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