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Anticorps Monoclonal anti-GUCY2C

GUCY2C Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1F5F6

N° de cat : 67782-1-PBS

Synonymes

GC C, Guanylyl cyclase C, GUC2C, GUCY2C, hSTAR, Intestinal guanylate cyclase, STA receptor, STAR

Galerie de données de validation

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  • Western Blot (WB) analysis of Caco-2 cells using GUCY2C Monoclonal antibody (67782-1-Ig)

    WB analysis of Caco-2 using 67782-1-Ig (same clone as 67782-1-PBS)

    Caco-2 cells were subjected to SDS PAGE followed by western blot with 67782-1-Ig (GUCY2C antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67782-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HaCaT cells using GUCY2C Monoclonal antibody (67782-1-Ig)

    WB analysis of HaCaT using 67782-1-Ig (same clone as 67782-1-PBS)

    HaCaT cells were subjected to SDS PAGE followed by western blot with 67782-1-Ig (GUCY2C antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67782-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HeLa cells using GUCY2C Monoclonal antibody (67782-1-Ig)

    WB analysis of HeLa using 67782-1-Ig (same clone as 67782-1-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 67782-1-Ig (GUCY2C antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67782-1-PBS in a different storage buffer formulation.

Informations sur le produit

67782-1-PBS cible GUCY2C dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Mouse / IgG1
Clonalité Monoclonal
Type Anticorps
Immunogène GUCY2C Protéine recombinante Ag19256
Nom complet guanylate cyclase 2C (heat stable enterotoxin receptor)
Masse moléculaire calculée 1073 aa, 123 kDa
Poids moléculaire observé130 kDa
Numéro d’acquisition GenBankBC136544
Symbole du gène GUCY2C
Identification du gène (NCBI) 2984
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine G
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

GUCY2C is also named as GUC2C, STAR(Heat-stable enterotoxin receptor), Guanylyl cyclase C and belongs to the adenylyl cyclase class-4/guanylyl cyclase family. It is a receptor for the E.coli heat-stable enterotoxin and considered to be the true apical membrane receptor for the endogenous ligands uroguanylin and guanylin. GUCY2C is not present in the endocrine pancreas, but is localized exclusively to the ductal system which fully corresponds to the GUCY2C activity detected in the exocrine ductal system, but particularly not in islets of Langerhans. GUCY2C with a molecular mass of 130 kDa is detected in pancreatic and intestinal extracts.(PMID:11431160). The full length protein is 123 kDa and has a signal peptide and nine glycosylation sites.

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