Anticorps Polyclonal de lapin anti-GYG1

GYG1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 12836-1-PBS

Synonymes

EC:2.4.1.186, glycogenin 1, Glycogenin-1, GN1, GN-1

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Galerie de données de validation

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  WB analysis using 12836-1-AP (same clone as 12836-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12836-1-AP (GYG1 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12836-1-PBS in a different storage buffer formulation.

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  WB analysis of human testis using 12836-1-AP (same clone as 12836-1-PBS)

  human testis tissue were subjected to SDS PAGE followed by western blot with 12836-1-AP (GYG1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12836-1-PBS in a different storage buffer formulation.

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  IHC staining of human thyroid cancer using 12836-1-AP (same clone as 12836-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 12836-1-AP (GYG1 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12836-1-PBS in a different storage buffer formulation.

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  IHC staining of human thyroid cancer using 12836-1-AP (same clone as 12836-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 12836-1-AP (GYG1 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12836-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse skeletal muscle using 12836-1-AP (same clone as 12836-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using 12836-1-AP (GYG1 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12836-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat skeletal muscle using 12836-1-AP (same clone as 12836-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat skeletal muscle tissue slide using 12836-1-AP (GYG1 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12836-1-PBS in a different storage buffer formulation.

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Informations sur le produit

12836-1-PBS cible GYG1 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: GYG1 Protéine recombinante Ag3583
• Nom complet: glycogenin 1
• Masse moléculaire calculée: 350 aa, 39 kDa
• Poids moléculaire observé: 39 kDa
• Numéro d’acquisition GenBank: BC031096
• Symbole du gène: GYG1
• Identification du gène (NCBI): 2992
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The GYG1 gene encodes glycogenin-1, a core protein in muscle glycogen particles. GYG1 is a glycosyltransferase that forms a short glucose polymer of approximately 10 glucose residues by autoglucosylation (PMID: 25272951 ). Cardiomyopathy and muscle weakness associated with muscle glycogen depletion can also be caused by impaired priming of glycogen synthesis due to inactivation of muscle glycogenin (glycogenin-1) (PMID: 20357282).

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