Anticorps Recombinant de lapin anti-Glutamate receptor 3/GluA3

Glutamate receptor 3/GluA3 Recombinant Antibody for WB, IHC, IF-P, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IF-P, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242392C11

N° de cat : 84885-4-PBS

Synonymes

GRIA3, 242392C11, GluA3, GluR 3, GLUR C

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Galerie de données de validation

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  WB analysis using 84885-4-RR (same clone as 84885-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84885-4-RR (Glutamate receptor 3/GluA3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84885-4-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 84885-4-RR (same clone as 84885-4-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 84885-4-RR (Glutamate receptor 3/GluA3 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84885-4-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 84885-4-RR (same clone as 84885-4-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 84885-4-RR (Glutamate receptor 3/GluA3 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84885-4-PBS in a different storage buffer formulation.

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  IF Staining of mouse brain using 84885-4-RR (same clone as 84885-4-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse brain tissue using Glutamate receptor 3/GluA3 antibody (84885-4-RR, Clone: 242392C11 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84885-4-PBS in a different storage buffer formulation.

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Informations sur le produit

84885-4-PBS cible Glutamate receptor 3/GluA3 dans les applications de WB, IHC, IF-P, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Glutamate receptor 3/GluA3 Protéine recombinante Ag30898
• Nom complet: glutamate receptor, ionotrophic, AMPA 3
• Masse moléculaire calculée: 101 kDa
• Poids moléculaire observé: 101 kDa
• Numéro d’acquisition GenBank: NM_007325
• Symbole du gène: GRIA3
• Identification du gène (NCBI): 2892
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. GRIA3 (Glutamate ionotropic receptor AMPA type subunit 3), also known as Glutamate receptor R3 or A3 (GluR3 or GluA3), is associated with X-linked intellectual disability (ID), dysmorphic features, and non-syndromic epilepsy(PMID: 32977175). GRIA3 also plays a role as a mediator of tumor progression in pancreatic cancer downstream CUX1(PMID: 20689760).

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