Anticorps Monoclonal anti-HBE1-Specific

HBE1-Specific Monoclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2C11G6

N° de cat : 66151-1-PBS

Synonymes

HBE1, Hemoglobin epsilon, 2C11G6, Epsilon globin, Epsilon-globin

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Galerie de données de validation

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  WB analysis of K-562 using 66151-1-Ig (same clone as 66151-1-PBS)

  K-562 cells were subjected to SDS PAGE followed by western blot with 66151-1-Ig (HBE1-Specific antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66151-1-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 66151-1-Ig (same clone as 66151-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 66151-1-Ig (HBE1-Specific antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66151-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66151-1-PBS cible HBE1-Specific dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: hemoglobin, epsilon 1
• Poids moléculaire observé: 16 kDa
• Numéro d’acquisition GenBank: NM_005330
• Symbole du gène: HBE1
• Identification du gène (NCBI): 3046
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The hemoglobin molecule is a tetramer consisting of two α-globin-like polypeptide chains and two β-globin-like chains. The human hemoglobin genes are expressed in a tightly developmentally controlled fashion.ε-globin (HBE1) is the predominantly expressed gene during the embryonic stage. The epsilon hemoglobin chain seems to be the best marker for fetal nucleated red blood cells (NRBCs). Anti-HBE1 may be used to label and isolate fetal cells from maternal blood and can be useful in prenatal diagnosis. This antibody specifically recognizes the HBE1 and doesn't cross-react with other globin chains.

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