Anticorps Polyclonal de lapin anti-HCN1

HCN1 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 55222-1-PBS

Synonymes

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1, HAC 2, Brain cyclic nucleotide-gated channel 1, BCNG-1

---

Galerie de données de validation

• 

  WB analysis of mouse brain using 55222-1-AP (same clone as 55222-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 55222-1-AP (HCN1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55222-1-PBS in a different storage buffer formulation.

• 

  IP experiment of mouse brain using 55222-1-AP (same clone as 55222-1-PBS)

  IP result of anti-HCN1 (IP:55222-1-AP, 4ug; Detection:55222-1-AP 1:1000) with mouse brain tissue lysate 4000ug. This data was developed using the same antibody clone with 55222-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human heart using 55222-1-AP (same clone as 55222-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart using 55222-1-AP (HCN1 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 55222-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human cerebellum using 55222-1-AP (same clone as 55222-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human cerebellum tissue slide using 55222-1-AP (HCN1 antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 55222-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

55222-1-PBS cible HCN1 dans les applications de WB, IHC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: hyperpolarization activated cyclic nucleotide-gated potassium channel 1
• Masse moléculaire calculée: 99 kDa
• Poids moléculaire observé: 99-120 kDa
• Numéro d’acquisition GenBank: NM_021072
• Symbole du gène: HCN1
• Identification du gène (NCBI): 348980
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

HCN1, also named as BCNG1, belongs to the potassium channel HCN family. It hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. HCN1 contributes to the native pacemaker currents in heart (If) and in neurons (Ih). It is activated by cAMP, and at 10-100 times higher concentrations, also by cGMP. HCN1 may mediate responses to sour stimuli.

{{ptg:RelatedPrimaryAntibodies}}