Anticorps Recombinant de lapin anti-HCN1

HCN1 Recombinant Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242254A1

N° de cat : 84845-3-PBS

Synonymes

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1, HAC 2, Brain cyclic nucleotide-gated channel 1, BCNG-1, 242254A1

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Galerie de données de validation

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  WB analysis using 84845-3-RR (same clone as 84845-3-PBS)

  Boiled and unboiled mouse brain tissue lysates were subjected to SDS PAGE followed by western blot with 84845-3-RR (HCN1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84845-3-PBS in a different storage buffer formulation.

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  IHC staining of mouse cerebellum using 84845-3-RR (same clone as 84845-3-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 84845-3-RR (HCN1 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84845-3-PBS in a different storage buffer formulation.

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Informations sur le produit

84845-3-PBS cible HCN1 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: hyperpolarization activated cyclic nucleotide-gated potassium channel 1
• Masse moléculaire calculée: 99 kDa
• Poids moléculaire observé: 99-120 kDa
• Numéro d’acquisition GenBank: NM_021072
• Symbole du gène: HCN1
• Identification du gène (NCBI): 348980
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

HCN1, also named as BCNG1, belongs to the potassium channel HCN family. It hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. HCN1 contributes to the native pacemaker currents in heart (If) and in neurons (Ih). It is activated by cAMP, and at 10-100 times higher concentrations, also by cGMP. HCN1 may mediate responses to sour stimuli.

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