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Anticorps Recombinant de lapin anti-HCN4

HCN4 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242695D11

N° de cat : 85222-4-PBS

Synonymes

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4, 242695D11

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using HCN4 Recombinant antibody (85222-4-RR)

    WB analysis using 85222-4-RR (same clone as 85222-4-PBS)

    Mouse brain tissue lysates were subjected to SDS PAGE followed by western blot with 85222-4-RR (HCN4 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85222-4-PBS in a different storage buffer formulation.

Informations sur le produit

85222-4-PBS cible HCN4 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

Réactivité Humain, souris
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène Peptide
Nom complet hyperpolarization activated cyclic nucleotide-gated potassium channel 4
Masse moléculaire calculée 129 kDa
Poids moléculaire observé 130 kDa
Numéro d’acquisition GenBankNM_005477
Symbole du gène HCN4
Identification du gène (NCBI) 10021
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine A
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

HCN4 belongs to the potassium channel HCN family. It hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions. HCN4 may contribute to the native pacemaker currents in heart (If) and in neurons (Ih). It is activated by cAMP. HCN4 may mediate responses to sour stimuli. (PMID:10228147). Defects in HCN4 are a cause of sick sinus syndrome type 2 (SSS2). Defects in HCN4 are the cause of Brugada syndrome type 8 (BRS8).

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