Anticorps Monoclonal anti-HDAC11

HDAC11 Monoclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1G12B5

N° de cat : 67949-1-PBS

Synonymes

FLJ22237, HD11, HDAC11, histone deacetylase 11

---

Galerie de données de validation

• 

  WB analysis using 67949-1-Ig (same clone as 67949-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67949-1-Ig (HDAC11 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67949-1-PBS in a different storage buffer formulation.

• 

  WB analysis of SKOV-3 using 67949-1-Ig (same clone as 67949-1-PBS)

  SKOV-3 cells were subjected to SDS PAGE followed by western blot with 67949-1-Ig (HDAC11 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67949-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 67949-1-Ig (same clone as 67949-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 67949-1-Ig (HDAC11 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67949-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 67949-1-Ig (same clone as 67949-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 67949-1-Ig (HDAC11 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67949-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human colon cancer using 67949-1-Ig (same clone as 67949-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 67949-1-Ig (HDAC11 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67949-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human colon cancer using 67949-1-Ig (same clone as 67949-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 67949-1-Ig (HDAC11 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67949-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human ovary tumor using 67949-1-Ig (same clone as 67949-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 67949-1-Ig (HDAC11 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67949-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human ovary tumor using 67949-1-Ig (same clone as 67949-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 67949-1-Ig (HDAC11 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67949-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

67949-1-PBS cible HDAC11 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: HDAC11 Protéine recombinante Ag28335
• Nom complet: histone deacetylase 11
• Masse moléculaire calculée: 347 aa, 39 kDa
• Poids moléculaire observé: 39 kDa
• Numéro d’acquisition GenBank: BC009676
• Symbole du gène: HDAC11
• Identification du gène (NCBI): 79885
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Histone deacetylases(HDAC) are a class of enzymes that remove the acetyl groups from the lysine residues leading to the formation of a condensed and transcriptionally silenced chromatin. At least 4 classes of HDAC were identified. HDAC11 belongs to Class IV HDACs. HDAC11 is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants. HDAC11 has 2 isoforms with the molecular mass of 33 and 39 kDa.

{{ptg:RelatedPrimaryAntibodies}}