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Anticorps Monoclonal anti-HDAC4-specific

HDAC4-specific Monoclonal Antibody for ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

ELISA

Conjugaison

Non conjugué

CloneNo.

4C3B9

N° de cat : 60105-1-Ig

Synonymes

Galerie de données de validation

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  • Western Blot (WB) analysis of human brain tissue using HDAC4-specific Monoclonal antibody (60105-1-Ig)

    WB analysis of human brain using 60105-1-Ig

    human brain tissue were subjected to SDS PAGE followed by western blot with 60105-1-Ig (HDAC4-specific antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

Applications testées

Dilution recommandée

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

60105-1-Ig cible HDAC4-specific dans les applications de ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Mouse / IgG1
Clonalité Monoclonal
Type Anticorps
Immunogène Peptide
Nom complet histone deacetylase 4
Masse moléculaire calculée 119 kDa
Numéro d’acquisition GenBankBC039904
Symbole du gène HDAC4
Identification du gène (NCBI) 9759
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Précipitation de l'acide caprylique/du sulfate d'ammonium
Tampon de stockage PBS avec azoture de sodium à 0,1 % et glycérol à 50 % pH 7,3
Conditions de stockageStocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA.

Informations générales

HDAC4, also named as HDACA, belongs to the histone deacetylase family. HDAC4 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC4 is Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. This antibody is a mouse monoclonal antibody raised against a peptide mapping within human HDAC4.

Publications

SpeciesApplicationTitle

Genes Dev

MEF2 transcription factors are key regulators of sprouting angiogenesis.

Authors - Natalia Sacilotto
View Article