Anticorps Monoclonal anti-HDAC9

HDAC9 Monoclonal Antibody for WB, ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

Publications(3)

CloneNo.

1G6C5

N° de cat : 67364-1-Ig

Synonymes

HD9, 1G6C5, EC:3.5.1.98, HDAC7, HDAC7B

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Galerie de données de validation

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  WB analysis using 67364-1-Ig

  Various lysates were subjected to SDS PAGE followed by western blot with 67364-1-Ig (HDAC9 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 67364-1-Ig

  Various lysates were subjected to SDS PAGE followed by western blot with 67364-1-Ig (HDAC9 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: cellules HeLa, cellules Daudi, cellules HepG2, cellules K-562, cellules Raji, cellules Ramos

Dilution recommandée

• Western Blot (WB): WB : 1:1000-1:4000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• WB: See 3 publications below

Informations sur le produit

67364-1-Ig cible HDAC9 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Réactivité citée: Humain
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: HDAC9 Protéine recombinante Ag28514
• Nom complet: histone deacetylase 9
• Masse moléculaire calculée: 1011 aa, 111 kDa
• Poids moléculaire observé: 130 kDa
• Numéro d’acquisition GenBank: BC152405
• Symbole du gène: HDAC9
• Identification du gène (NCBI): 9734
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

HDAC9, also named as Histone deacetylase 7B, is a 1011 amino acid protein, which is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. HDAC9 represses MEF2-dependent transcription. HDAC9 is broadly expressed, with highest levels in brain, heart, muscle and testis.

Publications

Species	Application	Title
human	WB	Int J Ophthalmol; Down-regulation of histone deacetylase 7 reduces biological activities of retinal microvascular endothelial cells under high glucose condition and related mechanism; Authors - Jia-Yi Ning
human	WB	Cell Death Dis; WNT5A promotes the metastasis of esophageal squamous cell carcinoma by activating the HDAC7/SNAIL signaling pathway.; Authors - Yingtong Feng
human	WB	Adv Sci (Weinh); N6-Methyladenosine Regulates Cilia Elongation in Cancer Cells by Modulating HDAC6 Expression; Authors - Yalan Rui

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