Anticorps Polyclonal de lapin anti-HEBP2

HEBP2 Polyclonal Antibody for WB, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 12706-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of human brain using 12706-1-AP (same clone as 12706-1-PBS)

  human brain tissue were subjected to SDS PAGE followed by western blot with 12706-1-AP (HEBP2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12706-1-PBS in a different storage buffer formulation.

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  WB analysis of human kidney using 12706-1-AP (same clone as 12706-1-PBS)

  human kidney tissue were subjected to SDS PAGE followed by western blot with 12706-1-AP (HEBP2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12706-1-PBS in a different storage buffer formulation.

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  IP experiment of HEK-293 using 12706-1-AP (same clone as 12706-1-PBS)

  IP result of anti-HEBP2 (IP:12706-1-AP, 3ug; Detection:12706-1-AP 1:500) with HEK-293 cells lysate 2400ug. This data was developed using the same antibody clone with 12706-1-PBS in a different storage buffer formulation.

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Informations sur le produit

12706-1-PBS cible HEBP2 dans les applications de WB, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: HEBP2 Protéine recombinante Ag3387
• Nom complet: heme binding protein 2
• Masse moléculaire calculée: 23 kDa
• Poids moléculaire observé: 23 kDa
• Numéro d’acquisition GenBank: BC008205
• Symbole du gène: HEBP2
• Identification du gène (NCBI): 23593
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

HEBP2(Heme-binding protein 2), also named SOUL and C6orf34, can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions (PMID: 17098234). It is a 23 kDa haem-binding protein that was first identified as the PP23 protein isolated from human full-term placentas. hEBP2 is essential for the proliferation of human cells and the repression of hEBP2 severely decreases the ability of EBNA1 and EBV-based plasmids to bind mitotic chromosomes (PMID: 15923612).

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