Anticorps Polyclonal de lapin anti-HIG2

HIG2 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 15587-1-PBS

Synonymes

C7orf68, HIG 2, HIG-2, HILPDA, Hypoxia-inducible gene 2 protein

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Galerie de données de validation

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  WB analysis using 15587-1-AP (same clone as 15587-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 15587-1-AP (HIG2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15587-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 15587-1-AP (same clone as 15587-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 15587-1-AP (HIG2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15587-1-PBS in a different storage buffer formulation.

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  IF Staining of A549 using 15587-1-AP (same clone as 15587-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed A549 cells using HIG2 antibody (15587-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 15587-1-PBS in a different storage buffer formulation.

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Informations sur le produit

15587-1-PBS cible HIG2 dans les applications de WB, IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: HIG2 Protéine recombinante Ag7829
• Nom complet: chromosome 7 open reading frame 68
• Masse moléculaire calculée: 7 kDa
• Poids moléculaire observé: 7-10 kDa
• Numéro d’acquisition GenBank: BC001863
• Symbole du gène: C7orf68
• Identification du gène (NCBI): 29923
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

HIG2 (Hypoxia inducible gene 2), also known as hypoxia inducible lipid droplet associated (HILPDA), is a gene that plays a significant role in the context of hypoxia, particularly in cancer biology. HIG2 is can be induced by hypoxia and glucose deprivation. It is expressed under low-oxygen conditions, which are common in the tumor microenvironment, and has been identified as a target gene of hypoxia-inducible factor-1 (HIF-1). HIG2 is implicated in the development and progression of various types of cancer, including renal cell carcinoma(PMID: 15930302), cell lymphoma(PMID: 26757780), epithelial ovarian cancer(PMID: 20134266), and uterine cancer(PMID: 21614900). Its expression is often elevated in these cancers and is associated with poor prognosis.

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