Anticorps Polyclonal de lapin anti-HIP14; ZDHHC17

HIP14; ZDHHC17 Polyclonal Antibody for WB, IHC, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, ELISA

Conjugaison

Non conjugué

N° de cat : 15465-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of Raji using 15465-1-AP (same clone as 15465-1-PBS)

  Raji cells were subjected to SDS PAGE followed by western blot with 15465-1-AP (HIP14; ZDHHC17 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15465-1-PBS in a different storage buffer formulation.

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  WB analysis of human kidney using 15465-1-AP (same clone as 15465-1-PBS)

  human kidney tissue were subjected to SDS PAGE followed by western blot with 15465-1-AP (HIP14; ZDHHC17 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15465-1-PBS in a different storage buffer formulation.

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  IHC staining of human testis using 15465-1-AP (same clone as 15465-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 15465-1-AP (HIP14; ZDHHC17 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 15465-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 15465-1-AP (same clone as 15465-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 15465-1-AP (HIP14; ZDHHC17 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 15465-1-PBS in a different storage buffer formulation.

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Informations sur le produit

15465-1-PBS cible HIP14; ZDHHC17 dans les applications de WB, IHC, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: HIP14; ZDHHC17 Protéine recombinante Ag7763
• Nom complet: zinc finger, DHHC-type containing 17
• Masse moléculaire calculée: 73 kDa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: BC050324
• Symbole du gène: ZDHHC17
• Identification du gène (NCBI): 23390
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Post-translational modification by the lipid palmitate is crucial for the correct targeting and function of many proteins. Polyglutamine expansions of huntingtin protein are responsible for the Huntington neurological disorder. ZDHHC17 gene encodes palmitoyl transferase huntingtin interacting protein (HIP14) which regulates palmitoylation and distribution of hungtingtin. The latter is implicated in the formation of inclusion bodies and enhanced neuronal toxicity. HIP14 was also shown to control neurotransmitter release.

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