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Anticorps Polyclonal de lapin anti-HIRA

HIRA Polyclonal Antibody for IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31152-1-PBS

Synonymes

Galerie de données de validation

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  • Immunoprecipitation (IP) experiment of HepG2 cells using HIRA Polyclonal antibody (31152-1-AP)

    IP experiment of HepG2 using 31152-1-AP (same clone as 31152-1-PBS)

    IP result of anti-HIRA (IP:31152-1-AP, 4ug; Detection:31152-1-AP 1:500) with HepG2 cells lysate 1600 ug. This data was developed using the same antibody clone with 31152-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of K-562 cells using HIRA Polyclonal antibody (31152-1-AP)

    IP experiment of K-562 using 31152-1-AP (same clone as 31152-1-PBS)

    IP result of anti-HIRA (IP:31152-1-AP, 4ug; Detection:31152-1-AP 1:500) with K-562 cells lysate 1600 ug. This data was developed using the same antibody clone with 31152-1-PBS in a different storage buffer formulation.

Informations sur le produit

31152-1-PBS cible HIRA dans les applications de IP, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène HIRA Protéine recombinante Ag34439
Nom complet HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
Masse moléculaire calculée 112 kDa
Poids moléculaire observé112 kDa
Numéro d’acquisition GenBankNM_003325
Symbole du gène HIRA
Identification du gène (NCBI) 7290
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

HIRA protein is encoded by a gene within a region of human chromosome 22q11.2 deleted in most patients with the DiGeorge syndrome, a developmental disorder, and was named for its amino acid sequence homology to two S. cerevisiae proteins, Hir1p and Hir2p. HIRA is critical in a specific chromatin assembly pathway that takes place independently of DNA synthesis (PMID: 12049744). HIRA complex associates with various proteins, such as transcription factors, RNA pol II, Prohibitin (PHB), and replication protein A (RPA) suggests that the targeting of the complex at specific locations may exploit additional structural properties and mechanisms (PMID: 30082790).

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